Overview

  • Product nameAnti-TXNRD2 antibody
    See all TXNRD2 primary antibodies
  • Description
    Rabbit polyclonal to TXNRD2
  • SpecificityAb16841 antibody is cross-reactive; it detects both TXNRD1 and TXNRD2. The antibody has been tested in western blotting in jurkat whole cell lysate, rat lung lysate, mouse liverlysate. In both rat and mouse lysates it detected two bands, the upper one being TXNRD2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein (Human).

  • Positive control
    • Jurkat whole cell lysate, rat lung lysate, mouse liver lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab16841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 56 kDa.

Target

  • FunctionMaintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
  • Tissue specificityHighly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
  • Sequence similaritiesBelongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • mitochondrial antibody
    • Selenoprotein Z antibody
    • SelZ antibody
    • Thioredoxin reductase 2 antibody
    • Thioredoxin reductase 2 mitochondrial antibody
    • Thioredoxin reductase 3 antibody
    • Thioredoxin reductase beta antibody
    • Thioredoxin reductase TR3 antibody
    • TR 3 antibody
    • TR antibody
    • TR beta antibody
    • TR-beta antibody
    • TR3 antibody
    • TRXR 2 antibody
    • TRXR2 antibody
    • TRXR2_HUMAN antibody
    • TXNRD 2 antibody
    • Txnrd2 antibody
    see all

Anti-TXNRD2 antibody images

  • All lanes : Anti-TXNRD2 antibody (ab16841) at 1/2000 dilution

    Lane 1 : Jurkat lysate
    Lane 2 : Mouse liver lysate
    Lane 3 : Rat lung lysate


    Predicted band size : 56 kDa


    In mouse and rat lysate the upper band is TXNRD2, we do not know what the lower non specific band is .

References for Anti-TXNRD2 antibody (ab16841)

This product has been referenced in:
  • Zhao X  et al. Variations of thioredoxin system contributes to increased susceptibility to apoptosis in cardiomyocytes of type 2 diabetic rats. Acta Biochim Biophys Sin (Shanghai) 46:318-29 (2014). Read more (PubMed: 24578161) »

See 1 Publication for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - other (Penile Tissue Homogenates)
Loading amount 20 µg
Specification Penile Tissue Homogenates
Gel Running Conditions Reduced Denaturing
Blocking step Starting Block T20 (PBS) as blocking agent for 30 minute(s) · Concentration: 100% · Temperature: 25°C
Username

Miss. gwen Lagoda

Verified customer

Submitted Jan 08 2010

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Rat Tissue lysate - whole (Penile Tissue)
Loading amount 60 µg
Specification Penile Tissue
Gel Running Conditions Reduced Denaturing (4-20% mini gel)
Blocking step Starting Block T20 (PBS) as blocking agent for 30 minute(s) · Concentration: 100% · Temperature: 25°C
Username

Miss. gwen Lagoda

Verified customer

Submitted Sep 09 2009

The laboratory has confirmed that the upper band in mouse and rat lysates is TXNRD2. We do not know the identity of the lower band, it may be another member of the TR family. This has now been clarified on the image. Please feel free to contact u...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"