Overview

  • Product nameAnti-TXNRD2 antibody
    See all TXNRD2 primary antibodies
  • Description
    Rabbit polyclonal to TXNRD2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human TXNRD2.

  • Positive control
    • This antibody gave a positive signal in the following human tissue lysates: Prostate; Liver; Testis.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab94522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

Target

  • FunctionMaintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
  • Tissue specificityHighly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
  • Sequence similaritiesBelongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • mitochondrial antibody
    • Selenoprotein Z antibody
    • SelZ antibody
    • Thioredoxin reductase 2 antibody
    • Thioredoxin reductase 2 mitochondrial antibody
    • Thioredoxin reductase 3 antibody
    • Thioredoxin reductase beta antibody
    • Thioredoxin reductase TR3 antibody
    • TR 3 antibody
    • TR antibody
    • TR beta antibody
    • TR-beta antibody
    • TR3 antibody
    • TRXR 2 antibody
    • TRXR2 antibody
    • TRXR2_HUMAN antibody
    • TXNRD 2 antibody
    • Txnrd2 antibody
    see all

Anti-TXNRD2 antibody images

  • All lanes : Anti-TXNRD2 antibody (ab94522) at 1 µg/ml

    Lane 1 : Human prostate tissue lysate (cirrhosis) - total protein (ab30307)
    Lane 2 : Human liver tissue lysate - total protein (ab29889)
    Lane 3 : Human testis tissue lysate - total protein (ab30257)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
    Additional bands at : 120 kDa,40 kDa,53 kDa (possible isoform). We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds

References for Anti-TXNRD2 antibody (ab94522)

ab94522 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94522.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"