Anti-Tyrosinase Related Protein 75 antibody (ab89635)

Overview

  • Product nameAnti-Tyrosinase Related Protein 75 antibody
    See all Tyrosinase Related Protein 75 primary antibodies
  • Description
    Mouse polyclonal to Tyrosinase Related Protein 75
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human protein (NP_000541.1)

  • Positive control
    • Pancreas or A431 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89635 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 61 kDa.

Target

  • FunctionOxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
  • Tissue specificityPigment cells.
  • PathwayPigment biosynthesis; melanin biosynthesis.
  • Involvement in diseaseDefects in TYRP1 are the cause of albinism oculocutaneous type 3 (OCA3) [MIM:203290]; also known as Rufous oculocutaneous albinism. An autosomal recessive disorder in which the biosynthesis of melanin pigment is reduced in skin, hair, and eyes. Tyrosinase activity is normal and patients have only moderate reduction of pigment. The eyes present red reflex on transillumination of the iris, dilution of color of iris, nystagmus and strabismus. Darker-skinned individuals have bright copper-red coloration of the skin and hair.
  • Sequence similaritiesBelongs to the tyrosinase family.
  • Cellular localizationMelanosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 6 dihydroxyindole 2 carboxylic acid oxidase antibody
    • 5 antibody
    • 6-dihydroxyindole-2-carboxylic acid oxidase antibody
    • Associated with iris pigmentation antibody
    • b protein antibody
    • CAS 2 antibody
    • CAS2 antibody
    • Catalase B antibody
    • CatalaseB antibody
    • CATB antibody
    • DHICA oxidase antibody
    • Glycoprotein 75 antibody
    • Glycoprotein75 antibody
    • gp75 antibody
    • Melanoma antigen gp75 antibody
    • OCA3 antibody
    • TRP 1 antibody
    • TRP 75 antibody
    • TRP antibody
    • TRP-1 antibody
    • TRP1 antibody
    • TRP75 antibody
    • Tyrosinase related protein 1 antibody
    • Tyrosinase-related protein 1 antibody
    • TYRP 1 antibody
    • TYRP antibody
    • TYRP1 antibody
    • TYRP1_HUMAN antibody
    • TYRRP antibody
    see all

Anti-Tyrosinase Related Protein 75 antibody images

  • Anti-Tyrosinase Related Protein 75 antibody (ab89635) at 1 µg/ml + Human pancreas lysate at 50 µg

    Predicted band size : 61 kDa
  • Anti-Tyrosinase Related Protein 75 antibody (ab89635) at 1 µg/ml + A431 cell lysate at 50 µg

    Predicted band size : 61 kDa
  • All lanes : Anti-Tyrosinase Related Protein 75 antibody (ab89635) at 1 µg/ml

    Lane 1 : Tyrosinase Related Protein 75 transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 61 kDa

References for Anti-Tyrosinase Related Protein 75 antibody (ab89635)

ab89635 has not yet been referenced specifically in any publications.

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