Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      RPSTSPCCPSSSTT
    • Amino acids
      474 to 487

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-TZFP antibody (ab26066)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • FANCC interacting protein
    • FANCC-interacting protein
    • Fanconi anemia zinc finger protein
    • FAXF
    • FAZF
    • OTTHUMP00000045790
    • repressor of GATA
    • Rog
    • Testis zinc finger protein
    • ZBT32_HUMAN
    • Zbtb32
    • ZBTB32 protein
    • Zinc finger and BTB domain containing 32
    • Zinc finger and BTB domain-containing protein 32
    • Zinc finger protein 538
    • ZNF538
    see all
  • Function
    DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells.
  • Tissue specificity
    Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
  • Sequence similarities
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 1 BTB (POZ) domain.
    Contains 3 C2H2-type zinc fingers.
  • Domain
    The C-terminal zinc finger domain functions as a transcriptional transactivator.
    The BTB (POZ) domain possesses repressor activity.
  • Cellular localization
    Nucleus. Located in nuclear speckles.
  • Information by UniProt

References

ab45517 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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