Overview

  • Product nameU 99194 maleate (PNU 99194)
  • Description
    Potent, selective D3 antagonist
  • Alternative names
    • PNU 99194
  • Biological descriptionPotent and selective D3 antagonist (Ki values are 160, 2281 and >10000 nM for hD3, D2 and D4 receptors, respectively).
  • Purity> 99%

Properties

    References for U 99194 maleate (PNU 99194) (ab120570)

    This product has been referenced in:
    • Li C  et al. Novel D3 dopamine receptor-preferring agonist D-264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and lactacystin. J Neurosci Res 88:2513-23 (2010). Read more (PubMed: 20623619) »
    • Casarrubea M  et al. Effects of 7-OH-DPAT and U 99194 on the behavioral response to hot plate test, in rats. Physiol Behav 89:552-62 (2006). Read more (PubMed: 16919688) »
    • Audinot V  et al. A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. J Pharmacol Exp Ther 287:187-97 (1998). Read more (PubMed: 9765337) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"