Overview

  • Product nameAnti-UAP1 antibody
    See all UAP1 primary antibodies
  • Description
    Rabbit polyclonal to UAP1
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow, Zebrafish
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 53-473 of UAP1 isoform AGX1 (Human)

  • Positive control
    • H1299 lysate, A549 cells (IF), and ES-2 xenograft (IHC)

Properties

Applications

Our Abpromise guarantee covers the use of ab95949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

Target

  • FunctionConverts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • Tissue specificityWidely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
  • PathwayNucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
  • Sequence similaritiesBelongs to the UDPGP type 1 family.
  • Cellular localizationCytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGX 1 antibody
    • AGX antibody
    • AGX-1 antibody
    • AGX-2 antibody
    • AGX1 antibody
    • Antigen X antibody
    • AntigenX antibody
    • SPAG 2 antibody
    • SPAG2 antibody
    • Sperm associated antigen 2 antibody
    • Sperm-associated antigen 2 antibody
    • UAP 1 antibody
    • uap1 antibody
    • UAP1_HUMAN antibody
    • UDP N acetylhexosamine pyrophosphorylase antibody
    • UDP N acteylglucosamine pyrophosphorylase 1 antibody
    • UDP-N-acetylglucosamine pyrophosphorylase antibody
    see all

Anti-UAP1 antibody images

  • Immunofluorescence analysis of paraformaldehyde fixed A549 cells using ab95949: (1) at 1/200 dilution, (2) merged with DNA probe.
  • Immunohistochemical analysis of paraffin embedded ES 2 xenograft using ab95949 at 1/500 dilution.
  • Anti-UAP1 antibody (ab95949) at 1/3000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 57 kDa

References for Anti-UAP1 antibody (ab95949)

ab95949 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"