• Product name
  • Description
    Mouse polyclonal to Ube2B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full-length Human Ube2B protein (AAH08470.1)

  • Positive control
    • Ube2B transfected 293T lysate and Jurkat cell lysate



Our Abpromise guarantee covers the use of ab92919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    WB: 1/500 - 1/1000. Predicted molecular weight: 17 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.
    • Pathway
      Protein modification; protein ubiquitination.
    • Sequence similarities
      Belongs to the ubiquitin-conjugating enzyme family.
    • Cellular localization
      Cell membrane. Nucleus. In peripheral neurons, expressed both at the plasma membrane and in nuclei.
    • Information by UniProt
    • Database links
    • Alternative names
      • E2 17kDa antibody
      • E2 protein antibody
      • hHR6B antibody
      • HR6B antibody
      • RAD6 homolog B antibody
      • RAD6B antibody
      • UBC2 antibody
      • UBE2B antibody
      • UBE2B_HUMAN antibody
      • Ubiquitin carrier protein B antibody
      • Ubiquitin conjugating enzyme E2 B antibody
      • Ubiquitin conjugating enzyme E2B (RAD6 homolog) antibody
      • Ubiquitin conjugating enzyme E2B antibody
      • Ubiquitin protein ligase B antibody
      • Ubiquitin-conjugating enzyme E2 17 kDa antibody
      • Ubiquitin-conjugating enzyme E2 B antibody
      • Ubiquitin-conjugating enzyme E2-17 kDa antibody
      • Ubiquitin-protein ligase B antibody
      see all

    Anti-Ube2B antibody images

    • Anti-Ube2B antibody (ab92919) at 500 µg + Jurkat cell lysate at 50 µg

      Predicted band size : 17 kDa
    • All lanes : Anti-Ube2B antibody (ab92919) at 1/500 dilution

      Lane 1 : Ube2B transfected 293T lysate
      Lane 2 : Non-transfected 293T lysate

      Lysates/proteins at 25 µg per lane.

      Predicted band size : 17 kDa
      Observed band size : 17 kDa

    References for Anti-Ube2B antibody (ab92919)

    ab92919 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92919.
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