FunctionAccepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesBelongs to the ubiquitin-conjugating enzyme family.
ab97279 at 1/200 dilution staining Ube2G2 in paraformaldehyde-fixed A549 cells by immunofluorescence. The lower image shows ab97279 merged with a DNA probe.
References for Anti-Ube2G2 antibody (ab97279)
This product has been referenced in:
Costa IM et al. The promoter of filamentation (POF1) protein from Saccharomyces cerevisiae is an ATPase involved in the protein quality control process. BMC Microbiol11:268 (2011).
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