• Product name
  • Description
    Goat polyclonal to Ube2L3
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Chicken, Cow, Xenopus laevis, Zebrafish
  • Immunogen

    Synthetic peptide:


    , corresponding to C terminal amino acids 142/154 of Human Ube2L3

  • Positive control
    • Hela and Jurkat lysates



Our Abpromise guarantee covers the use of ab37913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ELISA: antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
    • Tissue specificity
      Ubiquitous, with highest expression in testis.
    • Pathway
      Protein modification; protein ubiquitination.
    • Sequence similarities
      Belongs to the ubiquitin-conjugating enzyme family.
    • Post-translational
      Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation.
    • Cellular localization
      Nucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • E2 F1 antibody
      • L UBC antibody
      • L-UBC antibody
      • UB2L3_HUMAN antibody
      • UBCE7 antibody
      • UbcH7 antibody
      • UbcM4 antibody
      • Ube2l3 antibody
      • Ubiquitin carrier protein L3 antibody
      • Ubiquitin conjugating enzyme E2 L3 antibody
      • Ubiquitin protein ligase L3 antibody
      • Ubiquitin-conjugating enzyme E2 L3 antibody
      • Ubiquitin-conjugating enzyme E2-F1 antibody
      • Ubiquitin-protein ligase L3 antibody
      see all

    Anti-Ube2L3 antibody images

    • All lanes : Anti-Ube2L3 antibody (ab37913) at 0.03 µg/ml

      Lane 1 : Human skeletal muscle lysate
      Lane 2 : Mouse skeletal muscle lysate
      Lane 3 : Rat skeletal muscle lysate

      Lysates/proteins at 35 µg per lane.

      Predicted band size : 18 kDa
    • All lanes : Anti-Ube2L3 antibody (ab37913) at 0.01 µg/ml

      Lane 1 : Human heart lysate at 0.01 µg
      Lane 2 : Mouse heart lysate at 35 µg
      Lane 3 : Rat heart lysate at 35 µg
      Lane 4 : Pig heart lysate at 35 µg

      Predicted band size : 18 kDa
    • Anti-Ube2L3 antibody (ab37913) at 0.5 µg/ml + Hela lysate (RIPA buffer) at 35 µg
      Developed using the ECL technique

      Predicted band size : 18 kDa
      Observed band size : 18 kDa
      Primary incubated for 1 hour.

    References for Anti-Ube2L3 antibody (ab37913)

    This product has been referenced in:
    • Gandini MA  et al. The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels. Channels (Austin) 8:452-7 (2014). Read more (PubMed: 25483588) »
    • Reyes-Hernández OD  et al. Ube2l3 gene expression is modulated by activation of the aryl hydrocarbon receptor: implications for p53 ubiquitination. Biochem Pharmacol 80:932-40 (2010). WB ; Mouse . Read more (PubMed: 20478272) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab37913.
    Please use the links above to contact us or submit feedback about this product.


    Sign up