Anti-Ube2L3 antibody - N-terminal (ab71802)

Overview

  • Product name
    Anti-Ube2L3 antibody - N-terminal
    See all Ube2L3 primary antibodies
  • Description
    Rabbit polyclonal to Ube2L3 - N-terminal
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the N-terminal region of human Ube2L3 conjugated to KLH.

  • Positive control
    • Human breast carcinoma tissue. HL-60 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

Target

  • Function
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
  • Tissue specificity
    Ubiquitous, with highest expression in testis.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the ubiquitin-conjugating enzyme family.
  • Post-translational
    modifications
    Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • E2 F1 antibody
    • L UBC antibody
    • L-UBC antibody
    • UB2L3_HUMAN antibody
    • UBCE7 antibody
    • UbcH7 antibody
    • UbcM4 antibody
    • Ube2l3 antibody
    • Ubiquitin carrier protein L3 antibody
    • Ubiquitin conjugating enzyme E2 L3 antibody
    • Ubiquitin protein ligase L3 antibody
    • Ubiquitin-conjugating enzyme E2 L3 antibody
    • Ubiquitin-conjugating enzyme E2-F1 antibody
    • Ubiquitin-protein ligase L3 antibody
    see all

Images

  • Anti-Ube2L3 antibody - N-terminal (ab71802) at 1/100 dilution + HL-60 cell lysate at 12.5 µg

    Predicted band size : 18 kDa
    Observed band size : 18 kDa
    Additional bands at : 37 kDa,45 kDa,80 kDa. We are unsure as to the identity of these extra bands.
  • ab71802 at 1/50 dilution, staining Ube2L3 in formalin-fixed, paraffin-embedded human breast carcinoma tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

References

ab71802 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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