Overview

  • Product name
  • Description
    Rabbit polyclonal to UBIAD1
  • Specificity
    ab93413 reacts with residues 32-45 [PEQDRLPQRSWRQK] of UBIAD1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Reacts with residues 32-45 (

    PEQDRLPQRSWRQK

    ) of the 37kDa human TERE1 protein

Properties

Applications

Our Abpromise guarantee covers the use of ab93413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: 1/500. Predicted molecular weight: 37 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Prenyltransferase that mediates the formation of menaquinone-4 (MK-4), a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas. Mediates the conversion of phylloquinone (PK) into menaquinone-4 (MK-4), probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4.
    • Tissue specificity
      Ubiquitously expressed.
    • Pathway
      Cofactor biosynthesis; menaquinone biosynthesis.
    • Involvement in disease
      Defects in UBIAD1 are the cause of crystalline corneal dystrophy of Schnyder (SCCD) [MIM:121800]. SCCD is a rare autosomal dominant disease characterized by progressive corneal opacification resulting from abnormal deposition of cholesterol and phospholipids.
    • Sequence similarities
      Belongs to the ubiA prenyltransferase family.
    • Cellular localization
      Endoplasmic reticulum membrane. Cytoplasm. Nucleus. Mitochondrion.
    • Information by UniProt
    • Database links
    • Alternative names
      • RP4-796F18.1 antibody
      • SCCD antibody
      • TERE 1 antibody
      • tere1 antibody
      • Transitional epithelia response protein antibody
      • Transitional epithelial response protein 1 antibody
      • UbiA prenyltransferase domain containing 1 antibody
      • UbiA prenyltransferase domain containing protein 1 antibody
      • UbiA prenyltransferase domain-containing protein 1 antibody
      • UBIA1_HUMAN antibody
      • UBIAD 1 antibody
      • Ubiad1 antibody
      see all

    References for Anti-UBIAD1 antibody (ab93413)

    ab93413 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your reply.

    Can you describe the image that you had sent with the WB. Are the left 5 wells from rats with chronic kidney disease? Are the homogenates rat kidney? What are the control lanes?

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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