Human Predicted to work with:
Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
Synthetic peptide corresponding to a region within N terminal amino acids 143-192 (AVELLGDIVQ NCSLEDSQIE KERDVILREM QENDASMRDV VFNYLHATAF) of Human Ubiquinol-Cytochrome C Reductase Core Protein I (NP_003356).
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
FunctionThis is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
Sequence similaritiesBelongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.