Overview

  • Product name
  • Description
    Rabbit polyclonal to UBP43
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IF, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    QPRERPRAWD

    conjugated to KLH, corresponding to amino acids 40-49 of Human UBP43 (NP_059110.2).

  • Positive control
    • Human Heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 43 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.
ELISA 1/10000 - 1/50000.

Target

  • Function
    Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
  • Sequence similarities
    Belongs to the peptidase C19 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 43 kDa ISG15 specific protease antibody
    • 43 kDa ISG15-specific protease antibody
    • EC 3.1.2. antibody
    • hUBP43 antibody
    • Interferon Stimulated Gene 43 kD antibody
    • ISG15 Specific Processing Protease antibody
    • ISG15-specific-processing protease antibody
    • ISG43 antibody
    • Ubiquitin Specific Peptidase 18 antibody
    • Ubiquitin Specific Protease 18 43 kD antibody
    • Ubiquitin Specific Protease 18 antibody
    • Ubl carboxyl terminal hydrolase 18 antibody
    • Ubl carboxyl-terminal hydrolase 18 antibody
    • Ubl thioesterase 18 antibody
    • Ubl thiolesterase 18 antibody
    • Ubp15 antibody
    • UBP18_HUMAN antibody
    • USP18 antibody
    see all

Images

  • ab115618, at 5 µg/ml, staining UBP43 in Formalin-fixed, Paraffin-embedded Human heart tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115618 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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