This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

Applications

  • Application notes
    Tested in peptide ELISA.
    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
    • Sequence similarities
      Belongs to the peptidase C19 family.
    • Information by UniProt
    • Database links
    • Alternative names
      • 43 kDa ISG15 specific protease antibody
      • 43 kDa ISG15-specific protease antibody
      • EC 3.1.2. antibody
      • hUBP43 antibody
      • Interferon Stimulated Gene 43 kD antibody
      • ISG15 Specific Processing Protease antibody
      • ISG15-specific-processing protease antibody
      • ISG43 antibody
      • Ubiquitin Specific Peptidase 18 antibody
      • Ubiquitin Specific Protease 18 43 kD antibody
      • Ubiquitin Specific Protease 18 antibody
      • Ubl carboxyl terminal hydrolase 18 antibody
      • Ubl carboxyl-terminal hydrolase 18 antibody
      • Ubl thioesterase 18 antibody
      • Ubl thiolesterase 18 antibody
      • Ubp15 antibody
      • UBP18_HUMAN antibody
      • USP18 antibody
      see all

    Images

    This Fast-Track antibody is not yet fully characterised. These images represent inconclusive preliminary data.

    • Western blot using ab4188 at 1/500.

      Lane 1: Hela nuclear
      Lane 2: Hela
      Lane 3: A431
      Lane 4: Jurkat
      Lane 5: HEK293

      Secondary ab: Goat polyclonal to Rabbit IgG H&L (IR680) Pre-Adsorbed (1/5000)
      18µg of cell lysate per lane.

      Expected molecular weight: 43 kD.
      The strong band between the 37kD and 50kD markers is expected to be UBP43, however, we are not yet certain of this. The other bands are probably non-specific.

    References

    ab4188 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    The immunogen used in development of this antibody was purified human Factor VIII. The epitope recognized by this antibody is in the N-terminal region of the 83kDa light chain of...

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