Overview

  • Product nameAnti-UBXD2 antibody
  • Description
    Rabbit polyclonal to UBXD2
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide: RLPDGSSFTN QFPSDAPLEE ARQFAAQTVG NTYGNFSLAT MFPRREFTKE, corresponding to a region within internal sequence amino acids 325-374 of Human UBXD2

  • Positive control
    • HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab66010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 8 µg/ml.
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceUBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP) and promotes ER-associated protein degradation (ERAD). Immunohistochemical staining of brain tissue from patients with Alzheimer's disease and control subjects revealed that UBXD2 accumulates preferentially in neurons undergoing neurofibrillary degeneration in Alzheimer's disease.
  • Cellular localizationEndoplasmic reticulum membrane. Both the N- and the C-terminus face the cytosol; also found in the nucleus envelope contiguous to the ER.
  • Database links
  • Alternative names
    • Erasin antibody
    • FLJ23318 antibody
    • KIAA0242 antibody
    • KIAA2042 antibody
    • UBX domain containing 1 antibody
    • UBX domain containing 2 antibody
    • UBX domain containing protein 2 antibody
    • UBXD 2 antibody
    • UBXDC 1 antibody
    • UBXDC1 antibody
    see all

Anti-UBXD2 antibody images

  • Anti-UBXD2 antibody (ab66010) at 2.5 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • ab66010 at 8 µg/ml staining UBXD2 in Human kidney tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

References for Anti-UBXD2 antibody (ab66010)

ab66010 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab66010.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"