Overview

  • Product name
    Anti-UBXN6 antibody [2F8-24]
    See all UBXN6 primary antibodies
  • Description
    Mouse monoclonal [2F8-24] to UBXN6
  • Specificity
    Only detects the full-length isoform.
  • Tested applications
    Suitable for: WB, IP, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length Human protein

  • Positive control
    • U20S cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, 0.5% PBS, 0.1% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    2F8-24
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab81555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.
IP Use at 1-2 - 0.5 µg/mg of lysate.
ICC/IF Use a concentration of 0.05 - 0.5 µg/ml.

Target

  • Function
    Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.
  • Tissue specificity
    Enhanced expression in testis.
  • Sequence similarities
    Contains 1 PUB (PUG) domain.
    Contains 1 UBX domain.
  • Domain
    The UBX domain lacks key residues critical for VCP binding.
  • Cellular localization
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes at the centrosome both in interphase and during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • UBX domain containing 1 antibody
    • UBX domain containing 2 antibody
    • UBX domain containing protein 1 antibody
    • UBX domain containing protein 6 antibody
    • UBX domain protein 6 antibody
    • UBX domain-containing protein 1 antibody
    • UBX domain-containing protein 6 antibody
    • UBXD1 antibody
    • UBXDC2 antibody
    • Ubxn6 antibody
    • UBXN6_HUMAN antibody
    see all

Images

  • All lanes : Anti-UBXN6 antibody [2F8-24] (ab81555) at 1 µg/ml

    Lane 1 : U20S cells transfected with UBXN6 shRNA
    Lane 2 : U20S cells transfected with mismatch control shRNA


    Predicted band size : 50 kDa
    Observed band size : 54 kDa (why is the actual band size different from the predicted?)

References

ab81555 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab81555.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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