• Product name
    Anti-UCH37 antibody [EPR4896]
    See all UCH37 primary antibodies
  • Description
    Rabbit monoclonal [EPR4896] to UCH37
  • Host species
  • Tested applications
    Suitable for: WB, IP, IHC-P, Flow Cytmore details
    Unsuitable for: ICC
  • Species reactivity
    Reacts with: Rat, Human
    Does not react with: Mouse
  • Immunogen

    Synthetic peptide within Human UCH37 aa 1-100. The exact sequence is proprietary.

  • Positive control
    • Human fetal kidney, 293T, NCCIT and SH-SY5Y cell lysates; Human kidney tissue.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.


Associated products


Our Abpromise guarantee covers the use of ab124931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 36 kDa (predicted molecular weight: 38 kDa).
IP 1/10 - 1/100.
IHC-P 1/500 - 1/1000. Antigen retrieval is recommended. Heat up to 98 °C, below boiling, and then let cool for 10-20 min.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • Application notes
    Is unsuitable for ICC.
  • Target

    • Function
      Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.
    • Sequence similarities
      Belongs to the peptidase C12 family.
    • Cellular localization
      Cytoplasm. Nucleus. Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • UCH37 antibody
      • AD-019 antibody
      • CGI 70 antibody
      • INO80 complex subunit R antibody
      • INO80R antibody
      • Ubiquitin C terminal hydrolase L5 antibody
      • Ubiquitin C terminal hydrolase UCH37 antibody
      • Ubiquitin C-terminal hydrolase UCH37 antibody
      • Ubiquitin carboxyl terminal esterase L5 antibody
      • Ubiquitin carboxyl terminal hydrolase isozyme L5 antibody
      • Ubiquitin carboxyl terminal hydrolase L5 antibody
      • Ubiquitin carboxyl-terminal hydrolase isozyme L5 antibody
      • Ubiquitin thioesterase L5 antibody
      • Ubiquitin thiolesterase L5 antibody
      • UCH L5 antibody
      • UCH-L5 antibody
      • UCHL5 antibody
      • UCHL5_HUMAN antibody
      see all


    • All lanes : Anti-UCH37 antibody [EPR4896] (ab124931) at 1/1000 dilution

      Lane 1 : Human fetal kidney cell lysates
      Lane 2 : 293T cell lysates
      Lane 3 : NCCIT cell lysates
      Lane 4 : SH-SY5Y cell lysates

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 38 kDa

    • ab124931, at 1/500 dilution, staining UCH37 in paraffin embedded Human kidney tissue by Immunohistochemistry.


    This product has been referenced in:
    • Liao Y  et al. Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination. Oncogene 37:1896-1910 (2018). Human . Read more (PubMed: 29353883) »
    • Randles L  et al. The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression. J Biol Chem 291:8773-83 (2016). Read more (PubMed: 26907685) »

    See all 2 Publications for this product

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