Overview

  • Product name
    Anti-UCK antibody
  • Description
    Rabbit polyclonal to UCK
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Cow, Pig
  • Immunogen

    Synthetic peptide corresponding to Human UCK aa 132-162 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control
    • WB: HepG2 cell lysate and mouse cerebellum tissue lysate. IHC-P: Human breast carcinoma.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).

Target

  • Function
    Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
  • Tissue specificity
    Ubiquitous.
  • Pathway
    Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
    Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.
  • Sequence similarities
    Belongs to the uridine kinase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cytidine monophosphate kinase antibody
    • Cytidine monophosphokinase 1 antibody
    • Cytidylate kinase antibody
    • Deoxycytidylate kinase antibody
    • FLJ12255 antibody
    • OTTHUMP00000022400 antibody
    • OTTHUMP00000022401 antibody
    • OTTHUMP00000022403 antibody
    • OTTHUMP00000022404 antibody
    • RP11-334J6.5 antibody
    • UCK 1 antibody
    • uck1 antibody
    • UCK1_HUMAN antibody
    • UMP-CMP kinase antibody
    • Uridine monophosphokinase 1 antibody
    • Uridine-cytidine kinase 1 antibody
    • Uridine/cytidine kinase 1 antibody
    • URK1 antibody
    see all

Images

  • All lanes : Anti-UCK antibody (ab37600) at 1/100 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : Mouse cerebellum tissue lysate.


    Predicted band size : 22 kDa
    Observed band size : 22 kDa
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemical analysis of ICK1 expression in formalin-fixed, paraffin-embedded humna breast carcinoma tissue section using 1/50 ab37600.

References

ab37600 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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