Overview

  • Product nameUDP-glucose
  • Description
    Highly potent P2Y14 agonist
  • Alternative names
    • UDP-glc
    • Uridine 5'-diphosphoglucose
    • Uridine-diphosphate-glucose disodium salt
  • Biological descriptionHighly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).

Properties

  • Chemical nameUridine 5'-diphosphoglucose disodium salt
  • Molecular weight610.27
  • Chemical structureChemical Structure
  • Molecular formulaC15H22N2Na2O17P2
  • CAS Number28053-08-9
  • Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESO=C1C=CN(C(=O)N1)[C@@H]3O[C@H](COP(=O)(OP(=O)(O[C@@H]2OC(CO)[C@@H](O)[C@@H](O)[C@@H]2O)O[Na])O[Na])[C@@H](O)[C@H]3O
  • Source

    Synthetic

  • Research areas

    Associated products

    References for UDP-glucose (ab120384)

    This product has been referenced in:
    • Bassil AK  et al. UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms. Am J Physiol Gastrointest Liver Physiol 296:G923-30 (2009). Read more (PubMed: 19164486) »
    • Fricks IP  et al. Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems. J Pharmacol Exp Ther 330:162-8 (2009). Read more (PubMed: 19339661) »
    • Abbracchio MP  et al. Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci 24:52-5 (2003). Read more (PubMed: 12559763) »

    See 0 Publications for this product

    Product Wall

    Thank you for contacting us. I have heard back from the lab with the following information: "We can confirm that the UDP-glucose does contain small amounts of UDP as it is used in the synthesis of this compound. Based on the HPLC the level of UDP is ap...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"