UDP sodium salt (Uridine 5'-diphosphate) (ab120383)

Overview

  • Product name
    UDP sodium salt (Uridine 5'-diphosphate)
  • Description
    P2Y6 agonist. P2Y14 ligand.
  • Alternative names
    • Uridine 5'-diphosphate
  • Biological description
    Endogenous P2Y receptor agonist which preferentially activates P2Y6. Antagonist and agonist activities reported at human P2Y14 receptors. Potent full agonist at rat P2Y12 (EC50 = 350 nM).
  • Purity
    > 98%

Properties

  • Chemical name
    Uridine 5'-diphosphate sodium salt
  • Molecular weight
    470.11
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C9H11N2Na3O12P2
  • CAS Number
    21931-53-3
  • PubChem identifier
    88264
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    O=P(O[Na])(O[Na])OP(=O)(O[Na])OC[C@H]2O[C@@H](N1C=CC(=O)NC1=O)[C@H](O)[C@@H]2O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Carter RL  et al. Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor. Mol Pharmacol 76:1341-8 (2009). Read more (PubMed: 19759354) »
  • Fricks IP  et al. UDP is a competitive antagonist at the human P2Y14 receptor. J Pharmacol Exp Ther 325:588-94 (2008). Read more (PubMed: 18252808) »
  • Nicholas RA  et al. Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor. Mol Pharmacol 50:224-9 (1996). Read more (PubMed: 8700127) »

See 0 Publications for this product

Customer reviews and Q&As

Thank you for contacting us regarding the extinction coefficient of ab120383.

We don’t measure this data ourselves but a search of available information has pulled up the following:

absorbance max: 262 nm (pH 7)

&epsilo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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