Overview

  • Product nameAnti-UFD1L antibody [5e2]
    See all UFD1L primary antibodies
  • Description
    Mouse monoclonal [5e2] to UFD1L
  • Tested applicationsSuitable for: WB, IP, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human, Xenopus laevis
  • Immunogen

    Recombinant full length protein (Mouse) expressed in E coli.

Properties

Applications

Our Abpromise guarantee covers the use of ab52094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
ELISA
ICC/IF
  • Application notesELISA: Use at an assay dependent dilution.
    ICC/IF: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionEssential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures.
    • Tissue specificityFound in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney.
    • PathwayProtein degradation; proteasomal ubiquitin-dependent pathway.
    • Sequence similaritiesBelongs to the UFD1 family.
    • Cellular localizationNucleus. Cytoplasm > cytosol.
    • Information by UniProt
    • Database links
    • Alternative names
      • UB fusion protein 1 antibody
      • Ubiquitin fusion degradation 1 like (yeast) antibody
      • Ubiquitin fusion degradation 1 like antibody
      • Ubiquitin fusion degradation protein 1 homolog antibody
      • UFD1 antibody
      • UFD1_HUMAN antibody
      • UFD1L antibody
      see all

    References for Anti-UFD1L antibody [5e2] (ab52094)

    ab52094 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab52094.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"