Anti-Ulex Europaeus Lectin 1 antibody (ab50683)

Overview

  • Product nameAnti-Ulex Europaeus Lectin 1 antibody
  • Description
    Rabbit polyclonal to Ulex Europaeus Lectin 1
  • Tested applicationsSuitable for: Double Immunodiffusion, IHC-Pmore details
  • Species reactivity
    Reacts with Ulex Europaeus. Not yet tested in other species, but epithelia from other species may also react with the antibody.
  • Immunogen

    Full length native protein (purified) from gorse seeds

  • Positive control
    • Human tonsil.
  • General notes


    This antibody reacts with Ulex Europaeus Lectin 1 bound to human endothelial cells of normal and neoplastic blood and lymphatic vesicles. It also reacts with human epithelia such as in the colon, bronchus, epidermis, sweat gland ducts and hair follicles. It also reacts with for Ulex Europaeus Lectin 1 bound to vasclular endothelium and squamous epithelium of human tonsil. While erythrocytes may be stained, no other tonsilar elements are reactive with the antibody. This antibody may be useful in the detection of vascular tumors, the investigation of vascular invasion by tumor cells, for determination of Ulex Europaeus Lectin 1 binding to normal, embryonal, dysplastic and neoplastic epithelia and the study of storage diseases such as fucosidosis.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: Whole serum
  • PurityWhole antiserum
  • Purification notesThe antiserum has been treated to remove lipoproteins.
  • Primary antibody notesThis antibody reacts with Ulex Europaeus Lectin 1 bound to human endothelial cells of normal and neoplastic blood and lymphatic vesicles. It also reacts with human epithelia such as in the colon, bronchus, epidermis, sweat gland ducts and hair follicles. It also reacts with for Ulex Europaeus Lectin 1 bound to vasclular endothelium and squamous epithelium of human tonsil. While erythrocytes may be stained, no other tonsilar elements are reactive with the antibody. This antibody may be useful in the detection of vascular tumors, the investigation of vascular invasion by tumor cells, for determination of Ulex Europaeus Lectin 1 binding to normal, embryonal, dysplastic and neoplastic epithelia and the study of storage diseases such as fucosidosis.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab50683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Double Immunodiffusion 1/8.

5 µl of serially diluted antiserum is reacted against 5 µg of purified UEA-I.

IHC-P 1/500.

Target

  • RelevanceUlex Europaeus is a European gorse shrub with fragrant golden-yellow flowers. Ulex Europaeus-I Lectin is a 46 kDa glycoprotein known to interact with -L fucosyl residues in oligosaccharides present on the membranes of human blood group O erythrocytes, human endothelial cells and a variety of human and animal epithelial cells.
  • Cellular localizationCytoplasmic (probable)
  • Alternative names
    • Anti H(O) lectin 1 antibody
    • Anti H(O) lectin I antibody
    • UEA 1 antibody
    • UEA I antibody
    • UEA1 antibody
    • Ulex europaeus agglutinin antibody
    see all

References for Anti-Ulex Europaeus Lectin 1 antibody (ab50683)

This product has been referenced in:
  • Kanmogne GD  et al. Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells. Int J Nanomedicine 7:2373-88 (2012). Read more (PubMed: 22661891) »

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Thymus)
Specification Thymus
Fixative Acetone
Permeabilization No
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Abcam user community

Verified customer

Submitted Feb 22 2013

Thank you for contacting us in regards to ab50683. I have had a further look into this antibody and how it is generally used. Although I was not able to access the reference you specified I did find a few others that may be of interest to you. From...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"