• Product nameAnti-ULK3 antibody
    See all ULK3 primary antibodies
  • Description
    Rabbit polyclonal to ULK3
  • SpecificityDetects endogenous levels of total ULK3 protein.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from an internal region of Human ULK3, isoform 2.

  • Positive control
    • Human breast carcinoma tissue; 293 cell extracts.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.88% Sodium chloride, 49.1% PBS
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab111195 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab111195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 24 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • FunctionSerine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.
  • Tissue specificityWidely expressed. Highest levels observed in fetal brain. In adult tissues, high levels in brain, liver and kidney, moderate levels in testis and adrenal gland and low levels in heart, lung, stomach, thymus, prostate and placenta. In the brain, highest expression in the hippocampus, high levels also detected in the cerebellum, olfactory bulb and optice nerve. In the central nervous system, lowest levels in the spinal cord.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
    Contains 2 MIT domains.
    Contains 1 protein kinase domain.
  • Post-translational
    Autophosphorylated in vitro.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • FormThere are 3 isoforms produced by alternative splicing.
  • Alternative names
    • DKFZP434C131 antibody
    • FLJ90566 antibody
    • Serine/threonine-protein kinase ULK3 antibody
    • Ulk3 antibody
    • ULK3_HUMAN antibody
    • unc 51 like kinase 3 (C. elegans) antibody
    • Unc-51-like kinase 3 antibody
    see all

Anti-ULK3 antibody images

  • ab111195 at 1/50 dilution staining ULK3 in paraffin-embedded Human Breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.
  • All lanes : Anti-ULK3 antibody (ab111195) at 1/500 dilution

    Lane 1 : 293 cell extracts
    Lane 2 : 293 cell extracts with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 24 kDa

References for Anti-ULK3 antibody (ab111195)

ab111195 has not yet been referenced specifically in any publications.

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