Overview

  • Product name
    Anti-Ultraspiracle antibody
  • Description
    Rabbit polyclonal to Ultraspiracle
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Drosophila melanogaster
  • Immunogen

    Synthetic peptide derived from the N terminal domain of Ultraspiracle protein from Choristoneura fumiferana (Spruce budworm).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • Storage buffer
    Preservative: None
    Constituents: Whole serum
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/2000. Predicted molecular weight: 52 kDa.
ICC Use at an assay dependent dilution.

Target

  • Function
    Receptor for ecdysone. May be an important modulator of insect metamorphosis. Plays an important part in embryonic and post-embryonic development. Binds to ecdysone response elements (ECRES) such as in the promoter region of s15 chorion gene.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR2 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Domain
    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • 2C antibody
      • CF1 antibody
      • CG4380 antibody
      • Chorion factor 1 antibody
      • Chorion factor CF1 antibody
      • Dmel\CG4380 antibody
      • NR2B4 antibody
      • Nuclear receptor subfamily 2 group B member 4 antibody
      • Protein ultraspiracle antibody
      • USP antibody
      • USP_DROME antibody
      • X receptor at 2C antibody
      • XR2C antibody
      see all

    References

    This product has been referenced in:
    • Kreher J  et al. EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes. Nat Commun 8:14806 (2017). WB . Read more (PubMed: 28378812) »
    • Sharma V  et al. Functional male accessory glands and fertility in Drosophila require novel ecdysone receptor. PLoS Genet 13:e1006788 (2017). Read more (PubMed: 28493870) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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