Overview

  • Product nameAnti-UMPS antibody
    See all UMPS primary antibodies
  • Description
    Mouse monoclonal to UMPS
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLG, corresponding to amino acids 381-480 of Human UMPS

Properties

Applications

Our Abpromise guarantee covers the use of ab58082 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • PathwayPyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
      Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
    • Involvement in diseaseDefects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.
    • Sequence similaritiesIn the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
      In the C-terminal section; belongs to the OMP decarboxylase family.
    • Information by UniProt
    • Database links
    • Alternative names
      • ODC antibody
      • OMPdecase antibody
      • OPRT antibody
      • OPRTase antibody
      • Orotate phosphoribosyl transferase and orotidine 5' decarboxylase antibody
      • Orotate phosphoribosyltransferase antibody
      • Orotate phosphoribosyltransferase phosphoribosyltransferase antibody
      • Orotidine 5' phosphate decarboxylase antibody
      • Orotidine 5''-phosphate decarboxylase antibody
      • RP11-71H17.9 antibody
      • UMP synthase antibody
      • Umps antibody
      • UMPS_HUMAN antibody
      • Uridine 5' monophosphate synthase antibody
      • Uridine monophosphate synthetase antibody
      see all

    Anti-UMPS antibody images

    • Western blot against tagged recombinant protein immunogen using ab58082 UMPS antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-UMPS antibody (ab58082)

    ab58082 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab58082.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"