Overview

  • Product nameAnti-UNC13C antibody
  • Description
    Rabbit polyclonal to UNC13C
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Protein Epitope Signature Tag antigen: VLDELSVTYG ESFQVIIEEC IKQMSFELNQ MRANGNTTSN KNSAAMDAEI V, corresponding to amino acids 1838 - 1888 of Human UNC13C (Q8NB66).

  • Positive control
    • Human testis tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab122725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionProbably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
  • Tissue specificityExclusively expressed in brain.
  • Sequence similaritiesBelongs to the unc-13 family.
    Contains 2 C2 domains.
    Contains 1 MHD1 (MUNC13 homology domain 1) domain.
    Contains 1 MHD2 (MUNC13 homology domain 2) domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
  • DomainThe C2 domains are not involved in calcium-dependent phospholipid binding.
  • Cellular localizationCytoplasm. Membrane. Cell junction > synapse > presynaptic cell membrane. Localized to presynaptic structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp547H074 antibody
    • Munc13 3 antibody
    • Munc13-3 antibody
    • Protein unc-13 homolog C antibody
    • UN13C_HUMAN antibody
    • Unc13c antibody
    see all

Anti-UNC13C antibody images

  • ab122725, at 1/20 diltuion, staining UNC13C in paraffin-embedded Human testis tissue by Immunohistochemistry.

References for Anti-UNC13C antibody (ab122725)

ab122725 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - other (whole brain)
Loading amount 100 µg
Specification whole brain
Gel Running Conditions Reduced Denaturing (3.5% stacking gel, 7.5% running gel)
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 2% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Dec 21 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"