The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 103 kDa.
RelevanceUNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor and HSP90, and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]).
Cellular localizationCytoplasm. Cytoplasm, perinuclear region. Nucleus. Note: Predominant in the perinuclear region. Little protein in the nucleus.