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Rabbit polyclonal to UNC80
antigen sequence: KDSLNNVVDF LHALLGFCME PVTDNKAGFG NNFTTVDNKS TAQNVEGIIV SAMFKSLITR CASTTHELHS PENLGLYCDI RQLVQFIKEA HGNVFR, corresponding to amino acids of Human UNC80.
Human hippocampus tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium azide Constituents: 59% PBS, 40% Glycerol
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
Belongs to the unc-80 family.
Phosphorylated on tyrosine residues.
Information by UniProt
Protein unc-80 homolog antibody
UNC 80 antibody
This product has been referenced in:
et al. UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN. J Med Genet 53:397-402 (2016).
Read more (PubMed: 26545877) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"