Overview

  • Product name
  • Description
    Rabbit polyclonal to UNC93B
  • Specificity
    ab69497 will not crossreact with Unc93A.
  • Tested applications
    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 19 amino acid peptide from near the amino terminus of human UNC93B.

  • Positive control
    • Human heart tissue lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).

Target

  • Relevance
    UNC93B is a protein with similarity to the C. elegans unc93 protein. The Unc93 protein is involved in the regulation or coordination of muscle contraction in the worm. Defects in UNC93B are associated with susceptibility to herpes simplex encephalitis (HSE) which is a rare complication of human herpesvirus 1 (HHV-1) infection.
  • Cellular localization
    Membrane; Multi pass membrane protein
  • Database links
  • Alternative names
    • hUNC93B1 antibody
    • IIAE1 antibody
    • Protein unc 93 homolog B1 antibody
    • Protein UNC 93B antibody
    • unc 93 homolog B1 antibody
    • unc 93 homolog B1 (C elegans) antibody
    • unc 93 related protein antibody
    • Unc 93B1 antibody
    • unc93 (C elegans) homolog B antibody
    • unc93 (C elegans) homolog B1 antibody
    • UNC93 antibody
    • UNC93B antibody
    • UNC93B1 antibody
    see all

Anti-UNC93B antibody images

  • Lane 1 : Anti-UNC93B antibody (ab69497) at 0.5 µg/ml
    Lane 2 : Anti-UNC93B antibody (ab69497) at 1 µg/ml

    Lane 1 : human heart tissue lysate
    Lane 2 : human heart tissue lysate

    Lysates/proteins at 15 µg per lane.

    Secondary
    Anti-rabbit

    Predicted band size : 67 kDa
    Observed band size : 67 kDa
  • ab69497 at 2.5 µg/ml staining UNC93B in human heart tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

  • Immunofluorescence of Unc93b in Human Heart cells using ab69497 at 20 ug/ml.

References for Anti-UNC93B antibody (ab69497)

This product has been referenced in:
  • Garcia-Cattaneo A  et al. Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling. Proc Natl Acad Sci U S A 109:9053-8 (2012). Read more (PubMed: 22611194) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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