Overview

  • Product nameAnti-Unrip antibody
    See all Unrip primary antibodies
  • Description
    Rabbit polyclonal to Unrip
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    A region within synthetic peptide: LRLWQTVVGK TYGLWKCVLP EEDSGELAKP KIGFPETTEE ELEEIASENS, corresponding to C terminal amino acids 289-338 of Human Unrip

  • Positive control
    • HepG2 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab64424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionThe SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
  • Sequence similaritiesBelongs to the WD repeat STRAP family.
    Contains 7 WD repeats.
  • Cellular localizationCytoplasm. Nucleus. Localized predominantly in the cytoplasm but also found in the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • MAP activator with WD repeats antibody
    • MAWD antibody
    • PTWD antibody
    • Serine-threonine kinase receptor-associated protein antibody
    • serine/threonine kinase receptor associated protein antibody
    • strap antibody
    • STRAP_HUMAN antibody
    • UNR-interacting protein antibody
    • UNRIP antibody
    • WD 40 repeat protein PT WD antibody
    • WD-40 repeat protein PT-WD antibody
    see all

Anti-Unrip antibody images

  • Anti-Unrip antibody (ab64424) at 2.5 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 39 kDa
    Observed band size : 39 kDa

References for Anti-Unrip antibody (ab64424)

ab64424 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"