The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
Use at an assay dependent dilution.
1/50 - 1/100.
FunctionActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Tissue specificityExpressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.