Overview

  • Product name
    Anti-uPA Receptor antibody
    See all uPA Receptor primary antibodies
  • Description
    Goat polyclonal to uPA Receptor
  • Specificity
    ab52327 does not cross react with human tPA and human PAI-2.
  • Tested applications
    Suitable for: IHC-P, ELISA, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human Urokinase Plasminogen Activator-Receptor

Properties

Applications

Our Abpromise guarantee covers the use of ab52327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
ELISA Use at an assay dependent dilution.
IHC-Fr 1/50 - 1/100.

Target

  • Function
    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • Tissue specificity
    Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
  • Sequence similarities
    Contains 3 UPAR/Ly6 domains.
  • Cellular localization
    Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 87 antibody
    • CD87 antibody
    • CD87 antigen antibody
    • MO 3 antibody
    • MO3 antibody
    • Monocyte activation antigen Mo3 antibody
    • Plasminogen activator receptor urokinase antibody
    • Plasminogen activator urokinase receptor antibody
    • PLAUR antibody
    • U PAR antibody
    • u plasminogen activator receptor antibody
    • U-PAR antibody
    • u-plasminogen activator receptor form 2 antibody
    • UPA receptor antibody
    • uPAR antibody
    • UPAR_HUMAN antibody
    • Urinary plasminogen activator receptor antibody
    • URKR antibody
    • Urokinase plasminogen activator receptor antibody
    • Urokinase plasminogen activator surface receptor antibody
    • urokinase-type plasminogen activator (uPA) receptor antibody
    see all

References for Anti-uPA Receptor antibody (ab52327)

This product has been referenced in:
  • Yang D  et al. Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging. Oncotarget 7:73912-73924 (2016). ICC ; Human . Read more (PubMed: 27729618) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab52327.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up