Overview

  • Product name
    Anti-uPA Receptor antibody
    See all uPA Receptor primary antibodies
  • Description
    Goat polyclonal to uPA Receptor
  • Specificity
    ab52327 does not cross react with human tPA and human PAI-2.
  • Tested applications
    Suitable for: IHC-P, ELISA, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human Urokinase Plasminogen Activator-Receptor

Properties

Applications

Our Abpromise guarantee covers the use of ab52327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
ELISA Use at an assay dependent dilution.
IHC-Fr 1/50 - 1/100.

Target

  • Function
    Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
  • Tissue specificity
    Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
  • Sequence similarities
    Contains 3 UPAR/Ly6 domains.
  • Cellular localization
    Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 87 antibody
    • CD87 antibody
    • CD87 antigen antibody
    • MO 3 antibody
    • MO3 antibody
    • Monocyte activation antigen Mo3 antibody
    • Plasminogen activator receptor urokinase antibody
    • Plasminogen activator urokinase receptor antibody
    • PLAUR antibody
    • U PAR antibody
    • u plasminogen activator receptor antibody
    • U-PAR antibody
    • u-plasminogen activator receptor form 2 antibody
    • UPA receptor antibody
    • uPAR antibody
    • UPAR_HUMAN antibody
    • Urinary plasminogen activator receptor antibody
    • URKR antibody
    • Urokinase plasminogen activator receptor antibody
    • Urokinase plasminogen activator surface receptor antibody
    • urokinase-type plasminogen activator (uPA) receptor antibody
    see all

References

This product has been referenced in:
  • Yang D  et al. Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging. Oncotarget 7:73912-73924 (2016). ICC ; Human . Read more (PubMed: 27729618) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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