ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Tissue specificityExpressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
References for Anti-uPA Receptor antibody [MM0597-18L1] (ab89932)
This product has been referenced in:
Su B et al. Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches. Oncol Rep33:2484-94 (2015).
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