Overview

  • Product nameAnti-UPP2 antibody
    See all UPP2 primary antibodies
  • Description
    Rabbit polyclonal to UPP2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide between C terminal amino acids 217-244 of Human UPP2 (NP_775491.1), conjugated to KLH.

  • Positive control
    • Mouse heart tissue lysates; Human kidney carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab108049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 36 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionCatalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
  • Tissue specificityPredominantly expressed in kidney.
  • PathwayPyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
  • Sequence similaritiesBelongs to the PNP/UDP phosphorylase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Liver specific uridine phosphorylase antibody
    • UDRPASE2 antibody
    • UP2 antibody
    • UPase 2 antibody
    • UPASE2 antibody
    • UPP 2 antibody
    • UPP2 antibody
    • UPP2_HUMAN antibody
    • UrdPase 2 antibody
    • Uridine phosphorylase 2 antibody
    see all

Anti-UPP2 antibody images

  • Anti-UPP2 antibody (ab108049) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size : 36 kDa
  • ab108049, at a 1/50 dilution, staining UPP2 in formalin fixed, paraffin embedded Human kidney carcinoma by Immunohistochemistry, followed by peroxidase conjugation of the secondary antibody and DAB staining.

References for Anti-UPP2 antibody (ab108049)

ab108049 has not yet been referenced specifically in any publications.

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