Overview

  • Product name
    Anti-UPP2 antibody
  • Description
    Rabbit polyclonal to UPP2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-217 of Human UPP2.

  • Positive control
    • 293T, A431, HeLa and HepG2 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab153861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 36 kDa.

Target

  • Function
    Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
  • Tissue specificity
    Predominantly expressed in kidney.
  • Pathway
    Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
  • Sequence similarities
    Belongs to the PNP/UDP phosphorylase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • Liver specific uridine phosphorylase antibody
    • UDRPASE2 antibody
    • UP2 antibody
    • UPase 2 antibody
    • UPASE2 antibody
    • UPP 2 antibody
    • UPP2 antibody
    • UPP2_HUMAN antibody
    • UrdPase 2 antibody
    • Uridine phosphorylase 2 antibody
    see all

Images

  • All lanes : Anti-UPP2 antibody (ab153861) at 1/3000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 36 kDa



    10% SDS PAGE

References

ab153861 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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