Anti-UQCRC2 antibody [13G12AF12BB11] (ab14745)

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ab14745 has been referenced in 63 publications.

  • Gómez-Serrano M  et al. Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes. Redox Biol 11:415-428 (2017). WB ; Human . PubMed: 28064117
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  • Tezze C  et al. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. Cell Metab 25:1374-1389.e6 (2017). PubMed: 28552492
  • Newman LE  et al. The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS One 12:e0175164 (2017). PubMed: 28380071
  • Chiang SC  et al. Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage. Sci Adv 3:e1602506 (2017). PubMed: 28508041
  • Xie C  et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy 12:410-23 (2016). WB . PubMed: 26727396
  • Schubert C  et al. Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor ß. Biol Sex Differ 7:53 (2016). PubMed: 27688871
  • D'Andrea A  et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget 7:72415-72430 (2016). WB . PubMed: 27635472
  • Grünewald A  et al. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons. Ann Neurol 79:366-78 (2016). PubMed: 26605748
  • Münch C & Harper JW Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation. Nature 534:710-3 (2016). PubMed: 27350246
  • Thompson K  et al. Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number. Am J Hum Genet 99:860-876 (2016). PubMed: 27693233
  • Singh P  et al. Renal Mitochondrial Lipid Peroxidation during Sepsis. J Kidney 2:N/A (2016). PubMed: 27104220
  • Janer A  et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med 8:1019-38 (2016). PubMed: 27390132
  • Volonte D  et al. Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease. Aging (Albany NY) 8:2355-2369 (2016). PubMed: 27705926
  • Boominathan A  et al. Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant. Nucleic Acids Res N/A:N/A (2016). PubMed: 27596602
  • Chiu TW  et al. Hydrogen Sulfide Modulates the S-Nitrosoproteome and the Mitochondrial Morphology in Endothelial Cells. Acta Cardiol Sin 32:604-611 (2016). PubMed: 27713610
  • Anand R  et al. Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells. PLoS One 11:e0160258 (2016). WB . PubMed: 27479602
  • Quan X  et al. Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells. J Biol Chem 290:4086-96 (2015). WB ; Rat . PubMed: 25548283
  • Liu KM  et al. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Am J Physiol Renal Physiol 309:F318-31 (2015). WB ; Rat . PubMed: 26109091
  • Gouspillou G  et al. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep 5:8717 (2015). WB ; Mouse . PubMed: 25732599
  • Peng M  et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum Mol Genet 24:4829-47 (2015). WB . PubMed: 26041819
  • Jo A  et al. Efficient Mitochondrial Genome Editing by CRISPR/Cas9. Biomed Res Int 2015:305716 (2015). PubMed: 26448933
  • Hämäläinen RH  et al. mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling. Cell Rep 11:1614-24 (2015). WB . PubMed: 26027936
  • Vincent G  et al. Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51 (2015). WB . PubMed: 25759671
  • Nordsborg NB  et al. Oxidative capacity and glycogen content increase more in arm than leg muscle in sedentary women after intense training. J Appl Physiol (1985) 119:116-23 (2015). PubMed: 26023221
  • Alston CL  et al. A recessive homozygous p.Asp92Gly SDHD mutation causes prenatal cardiomyopathy and a severe mitochondrial complex II deficiency. Hum Genet 134:869-79 (2015). PubMed: 26008905
  • Nordby P  et al. Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial. J Appl Physiol (1985) 118:803-10 (2015). PubMed: 25614598
  • Guarani V  et al. TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex. Mol Cell Biol 34:847-61 (2014). PubMed: 24344204
  • Houštek J  et al. Effects of mtDNA in SHR-mtF344 versus SHR conplastic strains on reduced OXPHOS enzyme levels, insulin resistance, cardiac hypertrophy, and systolic dysfunction. Physiol Genomics 46:671-8 (2014). PubMed: 25073601
  • Yang CS  et al. The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy. Autophagy 10:785-802 (2014). PubMed: 24598403
  • Vega-Naredo I  et al. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells. Cell Death Differ : (2014). PubMed: 24832466
  • Wedding IM  et al. Spastic paraplegia type 7 is associated with multiple mitochondrial DNA deletions. PLoS One 9:e86340 (2014). IHC-Fr ; Human . PubMed: 24466038
  • Metodiev MD  et al. NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly. PLoS Genet 10:e1004110 (2014). WB ; Mouse . PubMed: 24516400
  • Huang R  et al. Megakaryocytic Differentiation of K562 Cells Induced by PMA Reduced the Activity of Respiratory Chain Complex IV. PLoS One 9:e96246 (2014). PubMed: 24817082
  • Miwa S  et al. Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice. Nat Commun 5:3837 (2014). PubMed: 24815183
  • Yarham JW  et al. Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA. PLoS Genet 10:e1004424 (2014). WB ; Human . PubMed: 24901367
  • Bannwarth S  et al. A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement. Brain 137:2329-45 (2014). Human . PubMed: 24934289
  • Wilson WC  et al. A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression. Hum Mol Genet N/A:N/A (2014). WB ; Human . PubMed: 25008111
  • Wanschers BF  et al. A mutation in the human CBP4 ortholog UQCC3 impairs complex III assembly, activity and cytochrome b stability. Hum Mol Genet N/A:N/A (2014). Human . PubMed: 25008109
  • Teh JT  et al. Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 0:N/A (2014). PubMed: 25151967
  • Hiniker A  et al. Axial mitochondrial myopathy in a patient with rapidly progressive adult-onset scoliosis. Acta Neuropathol Commun 2:137 (2014). IHC-Fr ; Human . PubMed: 25223649
  • Oláhová M  et al. A truncating PET100 variant causing fatal infantile lactic acidosis and isolated cytochrome c oxidase deficiency. Eur J Hum Genet N/A:N/A (2014). PubMed: 25293719
  • Chang HY  et al. Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells. Cell Death Dis 5:e1540 (2014). IF ; Human . PubMed: 25429617
  • Jacobs RA  et al. Fast-Twitch Glycolytic Skeletal Muscle Is Predisposed to Age-Induced Impairments in Mitochondrial Function. J Gerontol A Biol Sci Med Sci : (2013). PubMed: 23371970
  • Kumarasamy S  et al. Construction of two novel reciprocal conplastic rat strains and characterization of cardiac mitochondria. Am J Physiol Heart Circ Physiol 304:H22-32 (2013). WB ; Rat . PubMed: 23125210
  • Haack TB  et al. ELAC2 Mutations Cause a Mitochondrial RNA Processing Defect Associated with Hypertrophic Cardiomyopathy. Am J Hum Genet N/A:N/A (2013). WB ; Human . PubMed: 23849775
  • Palin EJ  et al. Mesencephalic complex I deficiency does not correlate with parkinsonism in mitochondrial DNA maintenance disorders. Brain 136:2379-92 (2013). Human . PubMed: 23811324
  • Habersetzer J  et al. Human F1F0 ATP Synthase, Mitochondrial Ultrastructure and OXPHOS Impairment: A (Super-)Complex Matter? PLoS One 8:e75429 (2013). WB ; Human . PubMed: 24098383
  • Hämäläinen RH  et al. Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model. Proc Natl Acad Sci U S A 110:E3622-30 (2013). PubMed: 24003133
  • Danhauser K  et al. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. Am J Hum Genet 91:1082-7 (2012). PubMed: 23141293
  • Haack TB  et al. Mutation screening of 75 candidate genes in 152 complex I deficiency cases identifies pathogenic variants in 16 genes including NDUFB9. J Med Genet 49:83-9 (2012). PubMed: 22200994
  • Blättler SM  et al. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor yin yang 1 in skeletal muscle. Mol Cell Biol 32:3333-46 (2012). Mouse . PubMed: 22711985
  • Houstek J  et al. Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics 44:487-94 (2012). WB ; Rat . PubMed: 22414913
  • Genda EN  et al. Co-compartmentalization of the Astroglial Glutamate Transporter, GLT-1, with Glycolytic Enzymes and Mitochondria. J Neurosci 31:18275-88 (2011). PubMed: 22171032
  • Danhauser K  et al. Cellular rescue-assay aids verification of causative DNA-variants in mitochondrial complex I deficiency. Mol Genet Metab 103:161-6 (2011). WB ; Human . PubMed: 21458341
  • Suthammarak W  et al. Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis elegans. J Biol Chem 285:40724-31 (2010). WB ; Caenorhabditis elegans . PubMed: 20971856
  • Suryawanshi AR  et al. Differential Proteomics Leads to Identification of Domain Specific Epididymal Sperm Proteins. J Androl : (2010). WB, ICC/IF ; Human, Rat . PubMed: 20966424
  • Escobar-Alvarez S  et al. Inhibition of human peptide deformylase disrupts mitochondrial function. Mol Cell Biol 30:5099-109 (2010). WB ; Human . PubMed: 20805355
  • Nakamura T  et al. Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells. Mol Neurodegener 4:35 (2009). WB ; Mouse . PubMed: 19695092
  • Powelka AM  et al. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest 116:125-36 (2006). WB ; Mouse . PubMed: 16374519
  • Martin K  et al. Simultaneous trichromatic fluorescence detection of proteins on Western blots using an amine-reactive dye in combination with alkaline phosphatase- and horseradish peroxidase-antibody conjugates. Proteomics 3:1215-27 (2003). PubMed: 12872222
  • Hanson BJ  et al. An immunocytochemical approach to detection of mitochondrial disorders. J Histochem Cytochem 50:1281-8 (2002). PubMed: 12364561
  • Martin K  et al. Simultaneous red/green dual fluorescence detection on electroblots using BODIPY TR-X succinimidyl ester and ELF 39 phosphate. Proteomics 2:499-512 (2002). PubMed: 11987124

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