Anti-Uridine Phosphorylase 1 antibody (ab185680)

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Overview

  • Product name
    Anti-Uridine Phosphorylase 1 antibody
    See all Uridine Phosphorylase 1 primary antibodies
  • Description
    Rabbit polyclonal to Uridine Phosphorylase 1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human Uridine Phosphorylase 1 aa 4-47 (N terminal).
    Sequence:

    TGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFP


    Database link: Q16831

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Human small intestine tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab185680 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
  • Pathway
    Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
  • Sequence similarities
    Belongs to the PNP/UDP phosphorylase family.
  • Information by UniProt
  • Database links
    • Alternative names
      • UDRPASE antibody
      • UP antibody
      • UPase 1 antibody
      • UPASE antibody
      • UPP antibody
      • Upp1 antibody
      • UPP1_HUMAN antibody
      • UrdPase 1 antibody
      • Uridine phosphorylase 1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uridine Phosphorylase 1 antibody (ab185680)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uridine Phosphorylase 1 antibody (ab185680)

      Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling Uridine Phosphorylase 1 with ab185680 at 1/50 dilution.

    References

    ab185680 has not yet been referenced specifically in any publications.

    Publishing research using ab185680? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    1 Review or Q&A

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    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-Uridine Phosphorylase 1 antibody

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    Abreviews
    Abcam has not validated the combination of species/application used in this Abreview.
    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample
    Baboon Tissue sections (Adult testis)
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Sodium citrate
    Permeabilization
    No
    Specification
    Adult testis
    Blocking step
    5% serum + 3% BSA as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: RT°C
    Fixative
    Paraformaldehyde
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    Submitted Mar 31 2017

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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