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Rabbit polyclonal to UROC1
Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 409-437 of Human UROC1 (NP_653240.1, NP_001159446.1).
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium Azide
Concentration information loading...
Immunogen affinity purified
ab107650 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 75 kDa.
Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.
Involvement in disease
Defects in UROC1 are a cause of urocanase deficiency (UROD) [MIM:276880]. An inborn error of histidine metabolism resulting in urocanic aciduria and neurological manifestations including mental retardation, ataxia, episodic aggressive behavior or exaggerated affection-seeking.
Belongs to the urocanase family.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"