Anti-Urocortin antibody (ab58459)
Key features and details
- Rabbit polyclonal to Urocortin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Urocortin antibody
See all Urocortin primary antibodies -
Description
Rabbit polyclonal to Urocortin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide derived from C-terminal of human urocortin.
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Positive control
- Human lung carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg+2 and Ca+2 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab58459 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
Target
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Function
Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. -
Sequence similarities
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 7349 Human
- Entrez Gene: 22226 Mouse
- Entrez Gene: 29151 Rat
- Omim: 600945 Human
- SwissProt: P55089 Human
- SwissProt: P81615 Mouse
- SwissProt: P55090 Rat
- Unigene: 534363 Human
see all -
Alternative names
- prepro-urocortin antibody
- Ucn antibody
- UCN1_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab58459 has been referenced in 2 publications.
- Antoniewicz J et al. Modulation of dermal equivalent of hypothalamus-pituitary-adrenal axis in mastocytosis. Postepy Dermatol Alergol 38:461-472 (2021). PubMed: 34377129
- Wierzbicka JM et al. Differentiation of Keratinocytes Modulates Skin HPA Analog. J Cell Physiol 232:154-66 (2017). PubMed: 27061711