The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: 1/10000. WB: 1/5000. Predicted molecular weight: 48 kDa. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Tissue specificityExpressed in the prostate gland and prostate cancers.
Sequence similaritiesBelongs to the peptidase S1 family. Contains 1 EGF-like domain. Contains 1 kringle domain. Contains 1 peptidase S1 domain.
Post-translational modificationsPhosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
Urokinase type plasminogen activator precursor antibody
Urokinase-type plasminogen activator chain B antibody
References for Anti-Urokinase antibody (ab20789)
This product has been referenced in:
Hasegawa Y et al. Urokinase-targeted fusion by oncolytic Sendai virus eradicates orthotopic glioblastomas by pronounced synergy with interferon-ß gene. Mol Ther18:1778-86 (2010).
Read more (PubMed: 20606645) »