Overview

  • Product nameAnti-USH1C antibody
    See all USH1C primary antibodies
  • Description
    Mouse monoclonal to USH1C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 424-534 of Human USH1C

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay be involved in protein-protein interaction.
    • Tissue specificityExpressed in small intestine, colon, kidney, eye and weakly in pancreas. Expressed also in vestibule of the inner ear.
    • Involvement in diseaseDefects in USH1C are the cause of Usher syndrome type 1C (USH1C) [MIM:276904]; also known as Usher syndrome type I Acadian variety. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH1 is characterized by profound congenital sensorineural deafness, absent vestibular function and prepubertal onset of progressive retinitis pigmentosa leading to blindness.
      Defects in USH1C are the cause of deafness autosomal recessive type 18 (DFNB18) [MIM:602092]. DFNB18 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
    • Sequence similaritiesContains 3 PDZ (DHR) domains.
    • DomainThe PDZ domain 1 mediates interactions with USH1G/SANS and SLC4A7.
    • Information by UniProt
    • Database links
    • Alternative names
      • AIE 75 antibody
      • AIE75 antibody
      • Antigen NY CO 38/NY CO 37 antibody
      • Antigen NY-CO-38/NY-CO-37 antibody
      • Autoimmune enteropathy related antigen AIE 75 antibody
      • Autoimmune enteropathy related antigen AIE75 antibody
      • Autoimmune enteropathy-related antigen AIE-75 antibody
      • Deafness autosomal recessive 18 antibody
      • DFNB 18 antibody
      • DFNB18 antibody
      • Harmonin antibody
      • NY CO 37 antibody
      • NY CO 38 antibody
      • PDZ 45 antibody
      • PDZ 73 antibody
      • PDZ 73 protein antibody
      • PDZ 73/NY CO 38 antibody
      • PDZ45 antibody
      • PDZ73 antibody
      • PDZ73 protein antibody
      • Protein PDZ-73 antibody
      • Renal carcinoma antigen NY REN 3 antibody
      • Renal carcinoma antigen NY-REN-3 antibody
      • USH 1C antibody
      • USH1C antibody
      • USH1C_HUMAN antibody
      • Ush1cpst antibody
      • Usher syndrome 1C (autosomal recessive severe) antibody
      • Usher syndrome 1C antibody
      • Usher syndrome type 1C protein antibody
      • Usher syndrome type-1C protein antibody
      see all

    Anti-USH1C antibody images

    • Western blot against tagged recombinant protein immunogen using ab56812 USH1C antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    References for Anti-USH1C antibody (ab56812)

    ab56812 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56812.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"