Overview

  • Product name
  • Description
    Rabbit polyclonal to USH1G
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IF, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human USH1G (internal sequence). The exact sequence is proprietary.
    Database link: Q495M9

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituents: 1.21% Tris, 0.75% Glycine
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 51 kDa.
ICC/IF 1/200 - 1/1000.
ICC 1/200 - 1/1000.

Target

  • Function
    Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
  • Tissue specificity
    Expressed in vestibule of the inner ear, eye and small intestine.
  • Involvement in disease
    Usher syndrome 1G
  • Sequence similarities
    Contains 3 ANK repeats.
    Contains 1 SAM (sterile alpha motif) domain.
  • Cellular localization
    Cytoplasm > cytosol. Cytoplasm > cytoskeleton. Cell membrane. Detected at the tip of cochlear hair cell stereocilia. Recruited to the cell membrane via interaction with CDH23 or PCDH15.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANKS 4A antibody
    • ANKS4A antibody
    • FLJ33924 antibody
    • SANS antibody
    • Scaffold protein containing ankyrin repeats and SAM domain antibody
    • USH 1G antibody
    • USH1G antibody
    • USH1G_HUMAN antibody
    • Usher syndrome 1G (autosomal recessive) antibody
    • Usher syndrome type 1G protein antibody
    • Usher syndrome type-1G protein antibody
    see all

References

ab196350 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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