The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
1/100 - 1/500. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa).
FunctionProtease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
Sequence similaritiesBelongs to the peptidase C19 family. Contains 1 DUSP domain.
Cellular localizationNucleus. Cytoplasm. Predominantly nuclear. Associates with chromatin.
ab71743 at 1/50 dilution, staining USP11 in human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.
References for Anti-USP11 antibody - C-terminal (ab71743)
has not yet been referenced specifically in any publications.
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