Overview

  • Product nameAnti-USP19 antibody
    See all USP19 primary antibodies
  • Description
    Mouse polyclonal to USP19
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full-length Human protein (NP_006668.1, aa 1-1318).

  • Positive control
    • USP19-transfected 293T cells lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab68527 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 175 kDa (predicted molecular weight: 145 kDa).

Target

  • FunctionDeubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
  • Sequence similaritiesBelongs to the peptidase C19 family.
    Contains 2 CS domains.
    Contains 1 MYND-type zinc finger.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 8430421I07Rik antibody
    • AI047774 antibody
    • Deubiquitinating enzyme 19 antibody
    • Ubiquitin carboxyl terminal hydrolase 19 antibody
    • Ubiquitin carboxyl-terminal hydrolase 19 antibody
    • Ubiquitin specific peptidase 19 antibody
    • Ubiquitin specific processing protease 19 antibody
    • Ubiquitin specific protease 19 antibody
    • Ubiquitin thioesterase 19 antibody
    • Ubiquitin thiolesterase 19 antibody
    • Ubiquitin-specific-processing protease 19 antibody
    • UBP19_HUMAN antibody
    • Usp19 antibody
    • Zinc finger MYND domain containing protein 9 antibody
    • Zinc finger MYND domain-containing protein 9 antibody
    • ZMYND9 antibody
    see all

Anti-USP19 antibody images

  • All lanes : Anti-USP19 antibody (ab68527) at 1/500 dilution

    Lane 1 : transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 145 kDa
    Observed band size : 175 kDa (why is the actual band size different from the predicted?)

References for Anti-USP19 antibody (ab68527)

ab68527 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab68527.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"