Overview

  • Product name
  • Description
    Rabbit polyclonal to USP19
  • Specificity
    USP19 antibody detects endogenous levels of total USP19 protein.
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human USP19

Properties

Applications

Our Abpromise guarantee covers the use of ab93159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
ELISA
  • Application notes
    ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 145 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates.
    • Sequence similarities
      Belongs to the peptidase C19 family.
      Contains 2 CS domains.
      Contains 1 MYND-type zinc finger.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 8430421I07Rik antibody
      • AI047774 antibody
      • Deubiquitinating enzyme 19 antibody
      • Ubiquitin carboxyl terminal hydrolase 19 antibody
      • Ubiquitin carboxyl-terminal hydrolase 19 antibody
      • Ubiquitin specific peptidase 19 antibody
      • Ubiquitin specific processing protease 19 antibody
      • Ubiquitin specific protease 19 antibody
      • Ubiquitin thioesterase 19 antibody
      • Ubiquitin thiolesterase 19 antibody
      • Ubiquitin-specific-processing protease 19 antibody
      • UBP19_HUMAN antibody
      • Usp19 antibody
      • Zinc finger MYND domain containing protein 9 antibody
      • Zinc finger MYND domain-containing protein 9 antibody
      • ZMYND9 antibody
      see all

    Images



    • Predicted band size : 145 kDa
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ab93159

    References

    This product has been referenced in:
    • Ogawa M  et al. 17ß-estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor a. J Biol Chem 286:41455-65 (2011). WB ; Mouse . Read more (PubMed: 21971047) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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