Anti-USP21 antibody (ab38864)


  • Product name
  • Description
    Rabbit polyclonal to USP21
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH selected from the C-terminal region of human USP21.

  • Positive control
    • Human breast carcinoma tissues.



Our Abpromise guarantee covers the use of ab38864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 63 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.


  • Function
    Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
  • Tissue specificity
    Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
  • Sequence similarities
    Belongs to the peptidase C19 family. USP21 subfamily.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Deubiquitinating enzyme 21 antibody
    • deubiquitinating enzyme 23 antibody
    • EC antibody
    • ESTM28 antibody
    • MGC3394 antibody
    • NEDD8-specific protease antibody
    • Ubiquitin carboxyl terminal hydrolase 21 antibody
    • ubiquitin carboxyl terminal hydrolase 23 antibody
    • Ubiquitin carboxyl-terminal hydrolase 21 antibody
    • ubiquitin specific peptidase 21 antibody
    • Ubiquitin specific processing protease 21 antibody
    • ubiquitin specific protease 16 antibody
    • ubiquitin specific protease 21 antibody
    • ubiquitin specific protease 23 antibody
    • Ubiquitin thioesterase 21 antibody
    • Ubiquitin thiolesterase 21 antibody
    • ubiquitin thiolesterase 23 antibody
    • ubiquitin-specific protease 23, formerly antibody
    • Ubiquitin-specific-processing protease 21 antibody
    • UBP21_HUMAN antibody
    • USP16 antibody
    • Usp21 antibody
    • USP23 antibody
    • USP23, formerly antibody
    • W53272 antibody
    see all

Anti-USP21 antibody images

  • Anti-USP21 antibody (ab38864) + T47D cell lysate

    Predicted band size : 63 kDa
  • Formalin fixed and paraffin embedded human breast carcinoma tissue stained with ab38864, followed by AEC staining.

References for Anti-USP21 antibody (ab38864)

ab38864 has not yet been referenced specifically in any publications.

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Abcam guarantees this product to work in the species/application used in this Abreview.
Western blot
Loading amount
0.034 µg
Catalytic domain of USP21
Gel Running Conditions
Non-reduced Denaturing (12)
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C
Human Purified protein (Catalytic domain of USP21)

Mr. Reggy Ekkebus

Verified customer

Submitted Jul 08 2010


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