Overview

  • Product nameAnti-USP3 antibody
    See all USP3 primary antibodies
  • Description
    Mouse monoclonal to USP3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: RNKVDTYVEF PLRGLDMKCY LLEPENSGPE SCLYDLAAVV VHHGSGVGSG HYTAYATHEG RWFHFNDSTV TLTDEETVVK AKAYILFYVE HQAKAGSDKL , corresponding to amino acids 421-521 of Human USP3

Properties

Applications

Our Abpromise guarantee covers the use of ab56901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionHydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.
    • Tissue specificityExpressed in all tissues examined, with strongest expression in pancreas.
    • Sequence similaritiesBelongs to the peptidase C19 family. USP3 subfamily.
      Contains 1 UBP-type zinc finger.
    • DomainBoth protease activity and an intact zinc finger are required for H2A monodeubiquitination.
    • Cellular localizationNucleus. Localizes preferentially with monoubiquitinated H2A to chromatin.
    • Information by UniProt
    • Database links
    • Alternative names
      • Deubiquitinating enzyme 3 antibody
      • EC 3.1.2.15 antibody
      • SIH003 antibody
      • Ubiquitin carboxyl-terminal hydrolase 3 antibody
      • Ubiquitin specific peptidase 3 antibody
      • Ubiquitin specific processing protease 3 antibody
      • Ubiquitin Specific Protease 3 antibody
      • Ubiquitin thioesterase 3 antibody
      • Ubiquitin thiolesterase 3 antibody
      • Ubiquitin-specific-processing protease 3 antibody
      • UBP antibody
      • UBP3_HUMAN antibody
      • Usp3 antibody
      see all

    Anti-USP3 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56901 USP3 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-USP3 antibody (ab56901)

    ab56901 has not yet been referenced specifically in any publications.

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