Overview

  • Product name
  • Description
    Rabbit polyclonal to USP36
  • Host species
    Rabbit
  • Specificity
    Reacts specifically with human 122 kDa USP36 protein
  • Tested applications
    Suitable for: IHC-Fr, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from internal domain of human USP36 protein

Properties

Applications

Our Abpromise guarantee covers the use of ab80260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/200 - 1/1000.
IHC-P 1/200 - 1/1000.
WB 1/500 - 1/5000. Detects a band of approximately 122 kDa.

Target

  • Function
    May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
  • Tissue specificity
    Broadly expressed.
  • Sequence similarities
    Belongs to the peptidase C19 family.
  • Cellular localization
    Nucleus > nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deubiquitinating enzyme 1 antibody
    • Deubiquitinating enzyme 36 antibody
    • DUB1 antibody
    • FLJ12851 antibody
    • KIAA1453 antibody
    • Ubiquitin carboxyl-terminal hydrolase 36 antibody
    • Ubiquitin specific peptidase 36 antibody
    • Ubiquitin specific processing protease 36 antibody
    • Ubiquitin thioesterase 36 antibody
    • Ubiquitin thiolesterase 36 antibody
    • Ubiquitin-specific-processing protease 36 antibody
    • UBP36_HUMAN antibody
    • Usp36 antibody
    see all

References

ab80260 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (HeLa)
Permeabilization
Yes - 0.5% Triton X-100
Specification
HeLa
Fixative
Paraformaldehyde
Username

Dr. Kirk Mcmanus

Verified customer

Submitted Jan 04 2018

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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