Overview

  • Product name
  • Description
    Rabbit polyclonal to USP46
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 240-269 of Human USP46 (NP_073743.2, NP_001127695.1).

  • Positive control
    • MDA-MB231 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab116312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

Target

  • Function
    Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
  • Tissue specificity
    Broadly expressed.
  • Sequence similarities
    Belongs to the peptidase C19 family. USP12/USP46 subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deubiquitinating enzyme 46 antibody
    • FLJ11850 antibody
    • FLJ12552 antibody
    • FLJ14283 antibody
    • FLJ39393 antibody
    • Ubiquitin carboxyl terminal hydrolase 46 antibody
    • Ubiquitin carboxyl-terminal hydrolase 46 antibody
    • Ubiquitin specific peptidase 46 antibody
    • Ubiquitin specific processing protease 46 antibody
    • Ubiquitin specific protease 46 antibody
    • Ubiquitin thioesterase 46 antibody
    • Ubiquitin thiolesterase 46 antibody
    • Ubiquitin-specific-processing protease 46 antibody
    • UBP46_HUMAN antibody
    • USP46 antibody
    see all

Images

  • Anti-USP46 antibody (ab116312) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

    Predicted band size : 42 kDa

References

ab116312 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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