FunctionDeubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Tissue specificityBroadly expressed.
Sequence similaritiesBelongs to the peptidase C19 family. USP12/USP46 subfamily.