Overview

  • Product nameAnti-USP46 antibody
    See all USP46 primary antibodies
  • Description
    Mouse polyclonal to USP46
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human USP46 protein (NP_073743.2).

  • Positive control
    • Human kidney tissue lysate. USP46 transfected 293T cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab88795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
ICC/IF Use at an assay dependent dilution.

Target

  • FunctionDeubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
  • Tissue specificityBroadly expressed.
  • Sequence similaritiesBelongs to the peptidase C19 family. USP12/USP46 subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deubiquitinating enzyme 46 antibody
    • FLJ11850 antibody
    • FLJ12552 antibody
    • FLJ14283 antibody
    • FLJ39393 antibody
    • Ubiquitin carboxyl terminal hydrolase 46 antibody
    • Ubiquitin carboxyl-terminal hydrolase 46 antibody
    • Ubiquitin specific peptidase 46 antibody
    • Ubiquitin specific processing protease 46 antibody
    • Ubiquitin specific protease 46 antibody
    • Ubiquitin thioesterase 46 antibody
    • Ubiquitin thiolesterase 46 antibody
    • Ubiquitin-specific-processing protease 46 antibody
    • UBP46_HUMAN antibody
    • USP46 antibody
    see all

Anti-USP46 antibody images

References for Anti-USP46 antibody (ab88795)

ab88795 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cultured Cells (MCF7)
Specification MCF7
Fixative Paraformaldehyde
Permeabilization Yes - 0.5% triton-x 10min
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 24°C
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Submitted Nov 08 2010

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - other (HELA)
Loading amount 30 µg
Specification HELA
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C
Username

Abcam user community

Verified customer

Submitted Nov 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"