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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.09% Sodium Azide
Constituents: Tris citrate/phosphate, pH 7-8
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab99946 was affinity purified using an epitope specific to USP6NL immobilized on solid support.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000 - 1/10000. Predicted molecular weight: 94 kDa.
Application notes Is unsuitable for IP.
Function Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Tissue specificity Widely expressed.
Sequence similarities Contains 1 Rab-GAP TBC domain.
Cellular localization Golgi apparatus. Cytoplasmic vesicle.
Information by UniProt
Related to the N terminus of tre antibody
Related to the N-terminus of tre antibody
Anti-USP6NL antibody images
References for Anti-USP6NL antibody (ab99946)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"