Overview

  • Product name
  • Description
    Rabbit polyclonal to USP6NL
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 350-400 of Human USP6NL (AAH42943.1).

  • Positive control
    • HeLa and 293T whole cell lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab99946 was affinity purified using an epitope specific to USP6NL immobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab99946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 94 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
    • Tissue specificity
      Widely expressed.
    • Sequence similarities
      Contains 1 Rab-GAP TBC domain.
    • Cellular localization
      Golgi apparatus. Cytoplasmic vesicle.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA0019 antibody
      • Related to the N terminus of tre antibody
      • Related to the N-terminus of tre antibody
      • RN tre antibody
      • RN-tre antibody
      • RNTRE antibody
      • TRE2NL antibody
      • US6NL_HUMAN antibody
      • USP6 N terminal like antibody
      • USP6 N terminal like protein antibody
      • USP6 N-terminal-like protein antibody
      • USP6NL antibody
      see all

    Images

    • All lanes : Anti-USP6NL antibody (ab99946) at 0.4 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg

      Developed using the ECL technique

      Predicted band size : 94 kDa


      Exposure time : 3 minutes

    References

    ab99946 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab99946.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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